REDWOOD CITY, Calif., April 24, 2024 (GLOBE NEWSWIRE) -- Coherus BioSciences, Inc. (Coherus, Nasdaq: CHRS) today announced the first presentation of clinical data for CHS-114, a highly selective ...

Conversely, although they detected cytolytic granules in the sera collected from the patient, suggesting that NK (natural ...

including enhancing the function of cytolytic T cells, a key component of the immune system responsible for attacking cancer ...

Cardiotropic viruses can cause pericardial and myocardial inflammation via direct cytolytic or cytotoxic effects and/or subsequent immune-mediated mechanisms. Many cases of myopericarditis are ...

CTLs and NK cells kill by forming a stereotyped interface with their targets, known as a cytolytic immunological synapse, into which they secrete a mixture of toxic perforin and granzymes. Our ...

Cytolytic peptides are small proteins that are drawn to cell membranes and destroy them by creating structural defects that cause the cells to break apart. The peptides have antibiotic ...

The human natural killer cell line, NK 3.3, is useful screening target for assessing the potential of therapeutic drug candidates to increase or decrease NK cell cytolytic function and for their ...

an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody, in children aged 6 to 11 years (N=28). At baseline, median blood eosinophil levels were 400 cells/µL in patients weighing less ...

The early data from Geneos Therapeutics shows that activated and cytolytic T cells were found in the tumor. These cells were primed by the vaccine antigens, which Sardesai says had been ...

Antigen-specific activation of Abecma results in CAR-positive T cell proliferation, cytokine secretion, and subsequent cytolytic killing of BCMA-expressing cells. The expanded approval was based ...