we have identified a novel cell surface maker that identifies foregut endoderm progenitors in pancreas and liver. We have shown that cells of the biliary reaction, a regenerative response to liver ...

Our focus is on the endoderm, the progenitor tissue that gives rise to respiratory and digestive tracts, and associated organs such as the lung, liver and pancreas. Our overarching goal is to ...

Turning off a gene early in mouse development led researchers to end up with an accidental six-legged embryonic mammal. This ...

After exposure to trans-retinoic acid, these cells can develop into two distinct forms of extra-embryonic endoderm. To date, differential library screening has been the best tool available to ...

Embryonic stem cells in culture are capable of self-renewal without differentiation and are able to differentiate into all cell types of the endoderm, mesoderm and ectoderm lineages using ...

Viotti M, Foley AC, Hadjantonakis AK. (2014) Gutsy moves in mice: cellular and molecular dynamics of endoderm morphogenesis. Philos Trans R Soc Lond B Biol Sci;369(1657). doi: 10.1098/rstb.2013.0547.

A complex interplay between the facial ectoderm, placodes, NCCs, neuroepithelium, and endoderm orchestrates accurate viscerocranium sculpting; this involves continuous expression changes in ...

Mar. 28, 2024 — Familial Alzheimer's disease can be transferred via bone marrow transplant, researchers show. When the team transplanted bone marrow stem cells from mice carrying a hereditary ...

Postdoctoral work in Harvard University (Cambridge, USA) where she developed interest in endoderm and pancreas development. In 2001, she started her lab on Pancreas Development and Cancer at the ISREC ...

More information: Seiichi Koike et al, Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells, eLife (2024). DOI: 10.7554/eLife.95999 ...