Further, they suppressed the secondary metabolic pathway of squalene synthase-ergosterol. This ergosterol pathway reduces the ...

Terbinafine, an allylamine antifungal, inhibits biosynthesis of ergosterol, an essential component of fungal cell membrane, via inhibition of squalene epoxidase enzyme. This results in fungal cell ...

Among their findings, they explain that the mushroom-contained bioactive compounds like cordycepin, lovastatin, eritadenine, and ergosterol are thought to “directly influence gene expression that ...

Vitamin D2 is synthetically made from radiating a compound (ergosterol) from the mold ergot. Vitamin D3 is made commercially and synthetically in a similar way that it is produced intrinsically in ...

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Blocks synthesis of ergosterol, a key component of the fungal cell membrane, through the inhibition of cytochrome P-450 dependent enzyme lanosterol 14α-demethylase responsible for the conversion ...

azoles inhibit the synthesis of ergosterol, the key fungal sterol; and 5-fluorocytosine is an inhibitor of fungal macromolecular synthesis. These agents were developed based on an understanding of ...

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Triazole antifungals are widely used and exert their action by inhibiting ergosterol biosynthesis. Here, Rybak et al show that these drugs both inhibit ergosterol biosynthesis and induce ...