In the fight to cure cancer, scientists need better models. And they might just get them — human-derived organoids — thanks ...

As a proof of concept, the team found that they could block the development of colorectal cancer in the minicolons by subduing an enzyme called glutathione peroxidase.

a groundbreaking method has been developed to assess the enzymatic activity of glutathione peroxidase 4 (GPX4), a pivotal regulator of ferroptosis." Ferroptosis works through excessive lipid ...

Heterozygous transgenic mice carrying the human glutathione peroxidase (GPx1) gene (16) were bred with Wt (CD1) mice to produce mixed litters of GPx1-overexpressing transgenic pups and Wt littermates.

The health industry is moving towards innovative solutions to health problems, and convenient solutions are replacing traditional methods. People want something quick and easy to boost their ...

Glutathione is a powerful antioxidant that the body naturally produces. It plays a vital role in protecting cells from the harmful effects and strain caused by free radicals. However, factors such ...

including glutathione peroxidase (GpX), after strenuous workouts compared to those who took a placebo. Continue reading Regularly incorporating pomegranate products into your diet, such as pomegranate ...

Antitumor responses and proper CD8 T-cell function also relies on the enzyme glutathione peroxidase 4 (GPX4), and increased GSH has been shown to prevent GPX4-dependent ferroptosis, a type of ...

J Biol Chem. 2005 Mar 25;280(12):11829-39. Epub 2005 Jan 10. Brenot A, King KY, Janowiak B, Griffith O, Caparon MG., Contribution of glutathione peroxidase to the virulence of Streptococcus pyogenes.

The tiny colons were grown from mouse stem cells, but human versions could one day be used to test new drugs for colorectal cancer, scientists say.