In this issue, Thepen and colleagues 1 have taken a more direct approach, targeting the macrophage itself for local apoptotic elimination, using an engineered immunotoxin. Taking advantage of the ...

The current research indicates that the chemical is likely a neurotoxin and immunotoxin, and can damage genes and cause birth defects as it moves through the bloodstream and settles into organs.

Denileukin diftitox (Ontak ®; Esai, Inc., Woodcliff Lake, NJ) is a chimeric immunotoxin composed of the modified cytotoxic domain of diphtheria toxin and human interleukin-2 (IL-2) protein.

Gunhan, E., P. Choudary, T.E. Landerholm and L.M. Chalupa; Depletion of cholinergic amacrine cells by a novel immunotoxin does not perturb the formation of segregated On and Off cone bipolar cell ...

A SOUTHAMPTON charity has made a major medical breakthrough that could revolutionise treating leukaemia patients and save thousands of lives. Scientists working for Leukaemia Busters have ...