Protein kinase inhibitors have been used in cancer treatment for more than two decades. They work by blocking the action of protein kinases, enzymes that control the function of proteins and can ...

JAK inhibitors are oral small-molecule drugs that block the action of JAK, a family of enzymes that help drive inflammation in the immune system. Scientists have identified four types of JAK ...

The entry inhibitor bulevirtide is the first and currently only approved drug (under the drug name Hepcludex) for the treatment of chronic infections with the hepatitis D virus. The active agent ...

Mechanism of action of the hepatitis B and D virus cell entry inhibitor bulevirtide deciphered. ScienceDaily . Retrieved April 29, 2024 from www.sciencedaily.com / releases / 2024 / 04 ...

ONO Pharmaceutical to acquire Deciphera Pharmaceuticals for $2.4B in cash. Deciphera brings specialized R&D in kinase drug ...

How does fluoxetine work (mechanism of action)? Fluoxetine is an antidepressant that belongs to a group of medicines called serotonin selective reuptake inhibitors (SSRIs). It works by increasing ...

An entirely new approach to inhibiting DNA-cleaving enzymes works through the aggregation of an otherwise non-toxic molecule.

This new agent, like the other DPP-4 inhibitors, has a mechanism of action that affects both pancreatic ß-cell survival as well as ß-cell secretory function. These medications do not incite ...

FDA approved Mirum Pharmaceuticals' Limvarli for treatment of cholestatic pruritus in patients with PFIC. Learn why I rate ...

Prioritization of Peak’s ADC cancer therapeutic platform technology and Akari’s PAS-nomacopan for Geographic Atrophy, a disabling ophthalmic ...