In the fight to cure cancer, scientists need better models. And they might just get them — human-derived organoids — thanks ...

The impact of intratumor heterogeneity on response and resistance to therapy is beginning to be understood; this information may prove crucial for the potentials of personalized medicine to be ...

Leading cancer researchers from UC San Francisco presented talks about advances in targeted therapy, cancer genomics, eliminating treatment disparities and other cancer research topics at this year’s ...

3 They found extensive intratumor heterogeneity of DNA methylation profiles, which reflect cellular states and provide evidence for epigenetic encoding. When classifying cells using previously ...

Should such a cure be found, it would be a thrilling result, but cancer is a group of many diseases that present differently and are subject to extensive intra- and intratumor heterogeneity.

The origins of cancer vaccines date back to the 1800s. Since then, there have been significant efforts to generate vaccines against solid and hematologic malignancies using a variety of platforms. To ...

The tiny colons were grown from mouse stem cells, but human versions could one day be used to test new drugs for colorectal cancer, scientists say.

Because the new organoid is more complex than previous models, scientists can study not only which cells give rise to colorectal cancer but also how the individual cells within those tumors differ ...