PIN1 is a member of the evolutionarily conserved peptidyl-prolyl isomerase family of proteins, which encompasses cyclophilins, FK506-binding proteins and parvulins. Unlike all other known prolyl ...

Lantern Pharma has entered into a partnership with Oregon Therapeutics for optimising the development of the cancer drug ...

The firms will use Lantern's AI platform to identify disease indications and biomarker signatures of response for Oregon's protein disulfide isomerase inhibitor.

Oregon Therapeutics & Lantern Pharma launch a strategic AI collaboration to optimize XCE853, a novel cancer drug candidate.

Amorolfine (or amorolfin), is a morpholine antifungal drug that inhibits Δ¹⁴-sterol reductase and cholestenol Δ-isomerase, which depletes ergosterol and causes ignosterol to accumulate in the ...

After the spontaneous development of arthritis in response to the ubiquitously expressed autoantigen glucose-6-phosphate isomerase (GPI), the mice received weekly injections of 1 mg rituximab.

Researchers at Duke University Medical Center discover a mechanism to enhance the fitness of cells against aging and neurodegenerative diseases. This finding will pave the way for novel therapeutic ...

Key areas of his work included: studying free-energy profiles of enzymes, defining the efficiency function (Ef) of enzymes in metabolic pathways, performing mutagenesis experiments to characterise the ...