CD7 expression is associated with poorer outcomes in patients with newly diagnosed acute myeloid leukemia (AML), according to ...

These findings were consistent with myelomonocytic leukemic infiltration of the colonic mucosa. Importantly, no evidence of acute blastic transformation was noted. The discovery of leukemic ...

Natural killer (NK) cells play a crucial role in cancer immunosurveillance. Circulating NK cells can kill target cells without prior sensitization. There are some receptors known to impact the ...

UGT2B17, a metabolic enzyme known for regulating various endogenous molecules, has been identified to have heightened ...

The IPSS gives a score based on three different factors: What percentage of immature white blood cells (also known as blast cells) in your bone marrow are leukemic, or abnormal. How many ...

Previous studies have shown the exhaustion of hematopoietic progenitor cells (HPCs) in leukemic marrow, whereas hematopoietic stem cells (HSCs) remain functional upon relocation to non-leukemic ...

has been limited the difficulty in identifying specific antigens that are expressed on AML and leukemic stem cells but not ...

MP0533 induces selective T cell-mediated killing of AML cell lines, as well as patient bone marrow-derived AML blasts and leukemic stem cells (LSCs) expressing two or three of the target antigens, ...

The Kharas lab is working to identify critical pathways in both normal and leukemic hematopoietic cells. MSK investigators have used a lab tool originally developed to study fly nerve cells to uncover ...

While the Dynamic International Prognostic Scoring System and bone marrow blasts may predict overall survival, the lack of ...

Inhibition of hsp70 synthesis as well as induction of apoptosis by treatment with quercetin combined with hyperthermia wss reported to be confined to leukemic cells, and not to normal hematopoietic ...