Levodopa-induced dyskinesia (LID) is a common complication after dopamine-replacement therapy in Parkinson's disease. The neural mechanisms underlying LID are far from clear, although significant ...

Despite the short half-life of levodopa, in early PD, the symptomatic benefit of levodopa/DDCI appears to last from dose to dose when administered on a three- or four-times daily schedule.

Deep brain stimulation is a game-changer for patients like Peters amid the ongoing fight for medical breakthroughs for ...

At 28 years old, Dr. Soania Mathur was building her medical practice and expecting her first child. Then she was diagnosed ...

‘The best drug to control Parkinson’s motor symptoms is levodopa, this is the backbone of treatment and has been around since the 1960s, but there are lots of other treatments we can use alongside to ...

US Neurologists express enthusiasm for new ways to administer current treatments and future disease modifying therapies, according to .Exton, Pennsylvania, May 09, 2024 (GLOBE NEWSWIRE) -- Even as the ...

Dopa-decarboxylase inhibitor + dopamine precursor. ≥18yrs: Do not crush or chew. Patients not receiving levodopa: initially one Sinemet CR 50–200 tab twice daily, at intervals of at least 6 hrs.

Subcutaneous infusion of ND0612 (a levodopa-carbidopa solution) increases on time without troublesome dyskinesia among patients with Parkinson disease, according to a study published online March ...

The treatment of Parkinson's disease (PD) focuses on improving symptoms and quality of life. Medication is the hallmark therapy, especially a drug called levodopa, which raises dopamine (a brain ...

A recent study in Nature Medicine evaluated the efficacy of prasinezumab, a monoclonal antibody, in slowing the progression of motor symptoms in Parkinson’s disease patients with rapidly ...

Stalevo® is a combination of levodopa, carbidopa and entacapone. It was initially approved based on pharmacokinetic studies demonstrating bioequivalence with Sinemet® immediate release (IR ...