Ligases are enzymes that catalyze the formation of chemical bonds, for instance C–O, C–N, C–S bonds, between two macromolecules, such as proteins or peptides, usually with accompanying ...

Accordingly, the total loss of DNA ligase function is lethal. DNA ligases catalyze the joining of a 5’-phosphate-terminated strand to a 3’-hydroxyl-terminated strand. Ligation depends on magnesium and ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

The financial injection was provided by venture capital entities M Ventures and MP Healthcare Venture Management.

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Q1 2024 Earnings Call Transcript May 2, 2024 Codexis, Inc. beats earnings expectations. Reported EPS is $-0.1647, ...

Outrun Therapeutics has launched with $10 million in seed financing. The company spun out of Satpal Virdee’s lab at the ...

Discovering new drug targets to combat antimicrobial resistance through innovative research and collaboration for global ...

Researchers developed a method to assess the ability of small molecules to bind to hundreds of human proteins using AI and ML ...

We have selected the protein group of RING type ubiquitin E3 ligases to assign them in plant developmental stages and organs by gene expression profiles, by high throughput phenotyping of ...

Ubiquitin ligases are enzymes involved in the ligation step of ubiquitylation. Ubiquitin ligases bind the substrate protein and catalyse the transfer of ubiquitin from the cysteine of ubiquitin ...