Felgner and colleagues developed the cationic lipid Lipofectin in 1987. Lipofectin–DNA complexes can be handled easily and, therefore, became one of the first chemical systems that could be used ...
Cationic charges in siRNA carriers can be provided by various materials, most typically polymers, lipids and inorganic nanomaterials. Inflammatory toxicity: lipoplexes are captured by Kupffer ...