A groundbreaking study has recognized the cGAS-STING signaling pathway as a formidable ally in the immune system's battle ...

Using machine learning to characterize the types of immune cells interacting in the microenvironment during active T-cell-mediated rejection episodes, the researchers found that regulatory (HLA ...

Colorectal cancer stands as one of the leading malignancies in the digestive system, ranking third and second in terms of new ...

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma ...

Scientists have discovered how glioblastoma evades the immune system by inducing pro-tumor macrophages via a glucose based epigenetic modification.

Until now, it has been poorly understood how monocyte-derived macrophages and microglia create an immunosuppressive tumor ...

In recent experiments, rat brain cells filled in for lost neurons in mouse brains, raising new possibilities for growing ...

Tumor microenvironment (TME) plays a pivotal role in malignant progression and metastatization in several tumors, including Bone and Soft Tissue Sarcoma (STS). Understanding the complexity of sarcomas ...

While immunotherapy has seen limited success in treating pancreatic cancer due to its immunosuppressive tumor microenvironment, it plays a crucial role in managing advanced stages of the disease.

A POSTECH research team have crafted a material aimed at swiftly staunching kidney bleeding and facilitating wound recovery.

A new study has revealed an association between favorable survival outcomes for melanoma patients and the presence of higher populations of tissue-resident memory T cells (TRM). Data obtained from ...

The project is aimed at developing novel approaches to enhance tumor immunogenicity to broaden the population of patients who ...