At the 2013 American College of Cardiology Scientific Sessions, results were presented from the first study of GGF2 in humans. In a phase 1 trial of 40 patients living with heart failure with a ...

Neuregulin 1, in particular the axon-associated type III isoform, has emerged as a signalling molecule of fundamental importance and considerable versatility, as it is likely to carry out ...

One mechanism has been identified in PNS myelination. In the PNS, neuregulin 1 type III protein is expressed on the axon surface and interacts with glial ErbB receptors, and it has a pivotal role ...

as well as in Phase 1/2 clinical trials for the treatment of solid tumors that harbor Neuregulin 1. The company is also developing MCLA-158, which is in a phase I clinical trial for the treatment ...

About ZenoZeno is an antibody-dependent cell-mediated cytotoxicity (ADCC)-enhanced Biclonics® that utilizes the Merus Dock & Block® mechanism to inhibit the neuregulin/HER3 tumor-signaling ...

Shenzhen Salubris commits additional funding to continue research and development of novel, complex biologics. First patient enrolled in RENEU-HF, the Phase 2 clinical trial of JK ...

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