Researchers say a promising new therapy targets protein clusters that likely cause neuron death and brain atrophy in ...

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and also collecting longitudinal clinical information to correlate with later neuropathologic findings, this approach will gather robust datasets not previously available from such a diverse ...

My academic interests include identifying biosignal correlates of neuropathologic symptoms and machine learning-based neural imaging classification.

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative ...

Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are sporadic four-repeat tauopathies that have characteristic clinical and neuropathologic profiles, but also share ...

The goals of the project are to determine whether the presence of atypical neuropathologic features may signal novel neurodegenerative disorders and whether each disorder is characterized by ...

In a pilot study, we used the Tau transgenic flies for functional validation of results from a genome-wide scan for AD neuropathologic burden. In 6 out of 15 genomic regions, we successfully ...

† Cognitive tests were not routinely conducted in all patients but only if indicated (number with cognitive deficit/number underwent cognitive tests suggested by American College of Rheumatology ...

Together with their colleagues in the UK, IU researchers used neuropathologic and molecular techniques and cutting-edge cryo-electron microscopy (cryo-EM) at atomic resolution to discover the ...