In a randomized, double-blind, placebo-controlled study, AZT + 3TC + abacavir performed well, but efavirenz-based therapy was even more effective. The appeal of triple-NRTI therapy with fixed-dose ...

Dr. Logue's research interests are in the application of organic synthesis to carbohydrates, C-nucleosides, and nucleotide analogues. C-nucleosides are nucleosides that contain a carbon - carbon ...

These molecules function to process rRNA molecules, often resulting in the methylation and pseudouridylation of specific nucleosides. These modifications are mediated by one of two classes of ...

Nucleobases are nitrogen-containing biological compounds that form nucleosides, which, in turn, are components of nucleotides, with all of these monomers formulate (i.e., the constitute) the basic ...

The other breakthrough was the discovery that substituted nucleosides incorporated into synthetic mRNA allow the molecule to enter cells in stealth mode, without triggering an innate immune ...

Then she and Weissman achieved a breakthrough. They modified the base components, or nucleosides, of mRNA, to avert an inflammatory response. Now, the molecule could get into cells to create ample ...

The don also noted that errors in HIV genetic materials and receptors are common factors too. Ogbonnanya, who was the former Dean, Faculty of Clinical Medicine, College of Health Sciences, Ebonyi ...

During this time, she was working on the synthesis of small molecules (nucleosides analogues) against viral infections in the group of Prof L. Agrofoglio. Alexandre joined the Royal Society of ...

BOC Sciences 2024 exhibition highlights include Nucleosides, Phosphoramidites, Inhibitors, Vaccine Adjuvants, RNAi Products, Impurities, Carbohydrates, and Building Blocks. And not just in complex ...

During this time, she was working on the synthesis of small molecules (nucleosides analogues) against viral infections in the group of Prof L. Agrofoglio. Catherine joined the Royal Society of ...

sugar protection protocols and synthetic manipulations); nucleosides and nucleotides (representation of DNA and RNA structures, the significance of the purine and pyrimidine ring systems noncovalent ...