Inside the cell nucleus, the DNA molecule is found in a densely packed DNA-protein complex known as chromatin. Here the DNA ...

The chain of nucleosomes is then compacted further and forms a highly organized complex of DNA and protein called a chromosome.

During DNA replication, parental nucleosomes carrying the epigenetic tags, also known as histone modifications, are ...

To this end, the DNA is wrapped around a core of histone proteins and densely packed to form nucleosomes. The structure of the nucleosomes determines which genes are accessible and active and ...

In the UK and throughout Europe, Antech, a division of Mars Science and Diagnostics, has introduced a novel cancer test for ...

VolitionRx Limited announced that its Nu. Q Vet Cancer Test is now available to veterinarians across the United States and ...

However, because all remodelers move nucleosomes and all such movement is ATP dependent, mobilization is most likely a property of the conserved ATPase subunit. The ATPase domains of remodelers ...

Kanazawa University report in Nano Letters how the use of high-speed atomic force microscopy helps to understand the crucial role played by certain biomolecules in DNA wrapping dynamics.

The most basic unit of DNA packaging is a wheel-shaped protein complex called the nucleosome. DNA strands wrap around nucleosomes like yarn around a spool. The more nucleosomes in a section of DNA, ...

Chromatin consists of nucleosomes, the basic structural unit of DNA packaging, and a series of nucleosomes connected by linker DNAs constitute chromatins. Regulatory proteins can reorganize chromatin ...

In eukaryotic cells, nucleosomes—composed of histone octamers—address the topological challenge of DNA packaging by condensing the DNA within the nucleus., crucial for genetic information ...