The primary stimulator of pericyte proliferation, however, is PDGF. Figure 3 depicts the ischemia-driven upregulation of VEGF, PDGF, FGF and Ang-2 and their target cells (stromal cells ...

Pericytes also migrate from the capillary fragments but under typical culture conditions approximately 20% of the seeded capillary fragments can generate pericyte-free endothelial cell colonies 72.

There is evidence that lower doses may be equally effective, especially in patients with less severe edema. [10] If beneficial, neurological improvement can be expected within 48 h with this ...

Physiol Rep. Feb;4, no. 3 (2016): pii: e12649. LaBarbera KE, Hyldahl RD, O'Fallon KS, Clarkson PM, Witkowski S. “Pericyte NF-κB activation enhances endothelial cell proliferation and proangiogenic ...

David Attwell at University College London, where I studied Brain Energy Supply and Use. During my PhD we demonstrated, for the first time, pericyte regulation of blood flow at the capillary level and ...

et al. Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. FASEB J. 18, 338–340 (2004).