Moreover, the newly identified pericyte-specific marker, Limb Bud-Heart (Lbh), in mouse and human cavernous tissues, clearly distinguishing pericytes from smooth muscle cells. Cell–cell interaction ...

Anita became passionate about cardiovascular biology during her time as a visiting student at the Bristol Royal Infirmary, studying pericyte metabolism in Type 2 diabetes. Driven by this enthusiasm, ...

VEGF stimulates development of the endothelial plexus, while PDGF induces pericyte recruitment to vascular endothelium, facilitating vessel maturation. Dual VEGF/PDGF therapies have been approved ...

Pericytes also migrate from the capillary fragments but under typical culture conditions approximately 20% of the seeded capillary fragments can generate pericyte-free endothelial cell colonies 72.

Division of Cardiology and Division of Cardiac Surgery, McGill University Health Centre, Montreal, Quebec, Canada ...

Normal tissue function depends on adequate supply of oxygen through blood vessels. Understanding how blood vessels form has become a principal, yet challenging, objective of the last decade.

Physiol Rep. Feb;4, no. 3 (2016): pii: e12649. LaBarbera KE, Hyldahl RD, O'Fallon KS, Clarkson PM, Witkowski S. “Pericyte NF-κB activation enhances endothelial cell proliferation and proangiogenic ...

There is evidence that lower doses may be equally effective, especially in patients with less severe edema. [10] If beneficial, neurological improvement can be expected within 48 h with this ...

2022). According to recent studies, low thrombin doses administered in the ICH rat model increase pericyte coverage by activating the angiopoietin receptor (Tie2) and downstream PI3K/Akt signaling, ...

Mounting evidence supports a key involvement of the chondroitin sulfate proteoglycans (CSPGs) NG2 and brevican (BCAN) in the regulation of axonal functions, including axon guidance, fasciculation, ...