The primary stimulator of pericyte proliferation, however, is PDGF. Figure 3 depicts the ischemia-driven upregulation of VEGF, PDGF, FGF and Ang-2 and their target cells (stromal cells ...

We and others showed that pericyte coverage significantly correlates with vascular integrity/function and intratumoral hypoxia. Therefore, understanding perivascular heterogeneity and the unique ...

While the role of ECs in tumor angiogenesis and the tumor microenvironment is well appreciated, pericyte function in tumors remains underexplored. In this study, we used pericyte-specific deletion of ...

While the role of ECs in tumor angiogenesis and the tumor microenvironment is well appreciated, pericyte function in tumors remains underexplored. In this study, we used pericyte-specific deletion of ...

We are interested in the role of stem cells in cell turnover in healthy and pathological situations. We study the identity of stem cells and the organization of cellular lineages, the molecular ...

We are studying homeostasis and tissue repair mechanisms in the mammalian system with a focus on perivascular cells, fibrosis and endogenous stem cells. The adult mammalian central nervous system (CNS ...

Institut de Génomique Fonctionnelle, Université de Montpellier, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Montpellier, France (T.M.-M.).

Traditionally, pericyte, served as capillary contraction handler, is recently considered as the main participant of microcirculation regulation in SAH pathophysiology (30). Although cerebral pericytes ...