The pharmacokinetics of promethazine hydrochloride after administration of rectal suppositories at three dosage strengths and oral syrup were studied. The study had an open-label, randomized ...

The purpose of this study was to evaluate the pharmacokinetics of intranasal hydromorphone hydrochloride (HCl) in patients with vasomotor rhinitis. Methods: Ten patients completed the randomised ...

The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

Sensei is conducting a multi-center Phase 1/2 clinical trial to evaluate the safety, tolerability, pharmacokinetics, ...

Neurocrine Biosciences Inc. has initiated its phase 1 clinical study, marking a significant stride in the evaluation of ...

Clinical-stage biotechnology company Acepodia has reported preliminary results from the Phase I study of anti-CD20 antibody ...

Ray Lambert looks at the potential of humanized FcRn mice for evaluating the pharmacokinetics of mAbs. Due to their extraordinary specificity and pharmacokinetic (PK) behavior, human ...

T he US Food and Drug Administration (FDA) has granted fast track designation for iECURE’s gene editing therapy, ECUR-506, ...

The study will assess the drug's safety, tolerability, pharmacokinetics and pharmacodynamics in obstructive HCM patients.

By Colin Kellaher Cytokinetics on Wednesday said an early study of its CK-586 potential treatment for a subgroup of heart-failure patients hit its key ...

in addition to assessments of safety and pharmacokinetics. Selected biomarkers, such as brain iron and aggregating α-synuclein, are important contributors to MSA pathology and are therefore ...

Completed enrollment in 60-patient Phase 1b/2 clinical studies of palazestrant in combination with each of ribociclib and palbociclibNew clinical ...