Little is known about presynaptic assembly during central nervous system synaptogenesis. Here we used time-lapse fluorescence imaging, immunocytochemistry and electron microscopy to study ...

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which affected the interaction of the protein with synaptotagmin 1 (Syt1), a calcium sensor protein located in the presynaptic membrane that is critical for CME. STON2 307Pro851Ala knockin mice ...

Their function is to take extra neurotransmitters from these synapses and transfer them back to presynaptic nerves for further use. Additionally, it should be noted that antidepressant medications ...

Summary: Atomoxetine is a methylphenoxy-benzenepropanamine derivative with antidepressant activity and is thought to enhance noradrenergic function via selective inhibition of the presynaptic ...

James McColl III and Lisa Tchitchkan were recognized as salutatorians April 2. USC announced its salutatorians for the Class ...

There are two types of removal: Re-uptake – the neurotransmitter is reabsorbed back into the presynaptic neuron and restored inside a vesicle ready to be used again. For example, noradrenaline.

Disturbed sleep is a prominent feature of fibromyalgia symptomatology and has been proposed as one of the core symptoms that should be systematically assessed in clinical trials for the treatment ...

Key steps include i) DNA end resection, ii) presynaptic filament assembly, iii) strand invasion/D-loop formation, iv) repair synthesis/D-loop extension and v) resolution of recombination intermediates ...

The mammalian brain is an extremely complex structure both anatomically and functionally, that simultaneously integrates multiple inputs to produce an appropriate response (Sillitoe, 2007; Joyner & ...

In conclusion, the results suggest that previously defined V1 clades show differences in birthdate, heterogeneity, projections to motoneurons and/or premotor networks, and collectively may represent ...