The prodrug is also engineered to optimize transport through liver cells, aiming to achieve a radical cure with a single dose ...

Reunion Neuroscience has cashed in on a $103 million series A, building on the promise of a phase 2-stage psychedelic prodrug ...

The company noted that the patent would cover composition of matter claims for a family of novel prodrug derivatives of psilocin which is different from a recently announced NOA for C4 ...

Hypoxia-activated prodrugs (HAPs) have the potential to activate specifically in hypoxic tumors and eliminate tumor cells, ...

Hypoxia-activated prodrugs (HAPs) have the potential to activate specifically in hypoxic tumors and eliminate tumor cells, which has brought new opportunities for safe and effective anticancer ...

Consequently, the success of prodrug strategies are very powerful means to improve formulation and delivery properties of drugs. However, prodrug intervention must be an integral part of the drug ...

Consider a patent which claims “administering drug X to a patient ….” Would administration of a prodrug, which is metabolized in a subject’s body to form drug X, infringe such a claim? Consider ...

The FDA approved pivmecillinam (Pivya) for the treatment of uncomplicated urinary tract infections (UTIs) in women caused by ...

The researchers therefore used a novel self-activating viridin (SAV) prodrug that slowly releases wortmannin. “The subsequent continuous generation of active wortmannin at a sustained level in ...

Company to present an update of its ongoing monotherapy and combination Phase 1/1b trial of WTX-124 in advanced or metastatic solid tumors at ASCO — — Company plans to present interim, first-in-human ...