Cutting-Edge Imaging Sheds New Light on Cells That Break Down Bone Oct. 26, 2023 — Imaging technology shows that bone-resorbing osteoclasts gather in distinct pockets, leading to new insights ...

Feb. 21, 2024 — With ever-increasing life expectancy comes the challenge of treating age-related disorders such as osteoporosis. Although there are effective drugs for treating this metabolic ...

Phosphorus works with calcium to impact bone-forming and bone-resorbing cell activity in a positive way. Research indicates that dairy products containing calcium and phosphorus can positively affect ...

The laboratory discovered that osteoclasts, in addition to their bone resorbing activity also are antigen presenting cells. He holds multiple patents on treatments for bone degeneration diseases.

In just 3 years, striking new advances have been made in understanding the molecular mechanisms that govern the crosstalk between osteoblasts/stromal cells and hemopoietic osteoclast precursor ...

a humanized monoclonal antibody that inhibits RANK-L (the ligand of receptor activator of nuclear factor-κB), thereby preventing osteoclast precursors from differentiating into bone-resorbing ...

DESPITE the heightened interest and work in bone physiology during the past decade (as indicated by a sudden increase in published textbooks and symposiums)it is probably fair to state that those ...

Osteoclasts are further activated to become mature bone-resorbing cells. RANKL produced from osteoblasts and osteocytes controls all of these processes. After osteoclasts finish bone resorption ...

In Hodgkin's disease, and in approximately one-third of cases of non-Hodgkin's lymphomas, hypercalcemia might occur as a result of vitamin D secretion or because of a bone-resorbing factor ...