Survivin is a functionally distinct member of the IAP family, with only a single BIR motif at its N-terminal half 9.The human survivin gene is abnormally over overexpressed in many forms of cancer ...

High survivin expression has been previously associated with aggressive tumor behavior, chemoresistance and poor clinical outcome in patients with liver, colorectal, breast, lung and esophageal ...

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The vaccine, called SurVaxM, targets a protein found in tumors called survivin, named for the role its thought to play in the survival of cancer cells. Get rid of survivin, the thinking goes ...

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Gualco E, Urbanska K, Perez-Liz G, Sweet T, Peruzzi F, Reiss K, and Del Valle L. IGF-1R dependent activation of Survivin is required for T-Antigen mediated protection from apoptosis and proliferation ...

Fenstermaker’s presentation centered on his work investigating the combination of SurVaxM, a peptide vaccine targeting survivin (a molecule highly expressed by glioblastoma cells), with adjuvant ...

BioVaxys has additionally announced it has entered the national phase also in Canada and Australia with its patent application for DPX-survivin/MAGE A9 ("DPX SurMAGE"), a DPX formulation of the ...