FactCheck.org. 30 Jul 2022. Sittplangkoon, Chutamath. “mRNA vaccine with unmodified uridine induces robust type I interferon-dependent anti-tumor immunity in a melanoma model.” Frontiers in Immunology ...

It was done by taking one of the RNA bases, uridine, and swapping in a very similar synthetic alternative. This breakthrough allowed scientists to create proteins in the body without the immune ...

Here’s where Karikó and Weissman come in. To investigate these problems, they synthesized mRNA in which they swapped out uridine, a typical building block of mRNA, for pseudouridine ...

In this article, we discuss the 25 richest billionaires in healthcare industry. To skip the detailed analysis of the ...

Pancreatic cancer cells can change their ‘diet’ to keep growing, by switching from the sugar glucose to a back-up fuel called uridine, new research reveals. The findings suggest that blocking the ...

A recently filed patent (Publication Number: US20230293567A1) describes a method for therapeutically improving and prolonging blood plasma uridine levels and tissue availability of uridine, as well as ...

Prelog also discussed personalized vaccines for cancer immunotherapy. Personalized mRNA vaccines are tailored to the ...

Scientists developed in vitro systems to carry out uridine deletion and insertion under controlled conditions in the laboratory to test both models, and the results favored the cleavage-ligation ...

They replaced one of mRNA’s four chemical building blocks, a nucleoside called uridine, with a slightly modified nucleoside called pseudouridine. This enabled the mRNA to skirt the body’s immune ...

UGT2B17, a metabolic enzyme known for regulating various endogenous molecules, has been identified to have heightened ...

Dolutegravir is not an inducer or inhibitor of CYP450 or uridine diphosphate glucuronosyltransferase enzymes and therefore is associated with few drug interactions other than metformin and dofetilide.