In the latest wave of attacks, Israel said it had struck Iran's Natanz and Isfahan nuclear sites. It initially said it had also hit Bushehr, site of Iran's only functioning nuclear power plant, but a spokesperson later said it was a mistake to have said this.

BEERSHEBA, Israel (AP) — Israel’s defense minister threatened Iran’s supreme leader on Thursday after the latest missile barrage from Iran damaged the main hospital in southern Israel and hit several other residential buildings near Tel Aviv. Israel meanwhile struck a heavy water reactor that is part of Iran’s nuclear program.

Israeli Defense Minister Israel Katz blamed Iranian Supreme Leader Ayatollah Ali Khamenei and said the military "has been instructed and knows that in order to achieve all of its goals, this man absolutely should not continue to exist.